The paediatric acute scrotum: are we still managing correctly?

Objective The objective of this study was to investigate current  investigation and management practice in a general district hospital in the UK of the paediatric acute scrotum. Summary background Diagnosis and  management of the paediatric acute scrotum remains an elusive and often challenging area of urology. In response to this, the urology team developed local guidelines to aid the management and treatment of this potentially life-changing condition.Patients and methods We reviewed the notes of allchildren (younger than 16 years of age) who presented  with a diagnosis of acute scrotum over a 2-year period in  Harrogate district hospital. We assessed the adherence to local guidelines, specifically the following: immediate urology review (within 1 h) and all patients with symptoms for less than 24 h should have immediate scrotal exploration. We also reviewed the discharge diagnosis.Results A total of 55 case notes were reviewed, of which 44 were eligible for data analysis; 23 patients were seen within an hour or under from the review request. In total, 21 patients were transferred to the theatre, with 19% having a final diagnosis of testicular torsion, yielding an overall incidence on the basis of eligible patients of 9%.Conclusion The paediatric acute scrotum is a potentially life-changing diagnosis, and timely review and action of management is important. Keywords: acute scrotum, paediatric, testicular torsion, time to theatre, ultrasound sca

A GPU-Oriented Algorithm Design for Secant-Based Dimensionality Reduction

Dimensionality-reduction techniques are a fundamental tool for extracting useful information from high-dimensional data sets. Because secant sets encode manifold geometry, they are a useful tool for designing meaningful data-reduction algorithms. In one such approach, the goal is to construct a projection that maximally avoids secant directions and hence ensures that distinct data points are not mapped too close together in the reduced space. This type of algorithm is based on a mathematical framework inspired by the constructive proof of Whitney's embedding theorem from differential topology. Computing all (unit) secants for a set of points is by nature computationally expensive, thus opening the door for exploitation of GPU architecture for achieving fast versions of these algorithms. We present a polynomial-time data-reduction algorithm that produces a meaningful low-dimensional representation of a data set by iteratively constructing improved projections within the framework described above. Key to our algorithm design and implementation is the use of GPUs which, among other things, minimizes the computational time required for the calculation of all secant lines. One goal of this report is to share ideas with GPU experts and to discuss a class of mathematical algorithms that may be of interest to the broader GPU community.Comment: To appear in the 17th IEEE International Symposium on Parallel and Distributed Computing, Geneva, Switzerland 201

High throughput genomic sequencing of bioaerosols in broiler chicken production facilities

Chronic inhalation exposure to agricultural dust promotes the development of chronic respiratory diseases among poultry workers. Poultry dust is composed of dander, chicken feed, litter bedding and microbes. However, the microbial composition and abundance has not been fully elucidated. Genomic DNA was extracted from settled dust and personal inhalable dust collected while performing litter sampling or mortality collection tasks. DNA libraries were sequenced using a paired-end sequencing-by-synthesis approach on an Illumina HiSeq 2500. Sequencing data showed that poultry dust is predominantly composed of bacteria (64–67%) with a small quantity of avian, human and feed DNA (\u3c 2% of total reads). Staphylococcus sp. AL1, Salinicoccus carnicancri and Lactobacillus crispatus were the most abundant bacterial species in personal exposure samples of inhalable dust. Settled dust had a moderate relative abundance of these species as well as Staphylococcus lentus and Lactobacillus salivarius. There was a statistical difference between the microbial composition of aerosolized and settled dust. Unlike settled dust composition, aerosolized dust composition had little variance between samples. These data provide an extensive analysis of the microbial composition and relative abundance in personal inhalable poultry dust and settled poultry dust

Evolving Techniques in Pancreatic Surgery

Diseases of the pancreas and periampullary region form an important clinical group of malignant and also benign diseases which still carry relatively high morbidity and mortality rates. Pancreatic ductal adenocarcinoma, in particular, is associated with very poor outcome as the number of new cases per year is just slightly higher than the number of deaths from this disease. Therefore, treatment of these conditions should always be based on both the highest level of evidence and technical expertise

Real-time human action recognition on an embedded, reconfigurable video processing architecture

Copyright @ 2008 Springer-Verlag.In recent years, automatic human motion recognition has been widely researched within the computer vision and image processing communities. Here we propose a real-time embedded vision solution for human motion recognition implemented on a ubiquitous device. There are three main contributions in this paper. Firstly, we have developed a fast human motion recognition system with simple motion features and a linear Support Vector Machine (SVM) classifier. The method has been tested on a large, public human action dataset and achieved competitive performance for the temporal template (eg. “motion history image”) class of approaches. Secondly, we have developed a reconfigurable, FPGA based video processing architecture. One advantage of this architecture is that the system processing performance can be reconfiured for a particular application, with the addition of new or replicated processing cores. Finally, we have successfully implemented a human motion recognition system on this reconfigurable architecture. With a small number of human actions (hand gestures), this stand-alone system is performing reliably, with an 80% average recognition rate using limited training data. This type of system has applications in security systems, man-machine communications and intelligent environments.DTI and Broadcom Ltd

Increased Physical Activity and Reduced Pain with Spinal Cord Stimulation: a 12-Month Study

International Journal of Exercise Science 13(3): 1583-1594, 2020. The purpose of this study was to assess changes in pain and physical activity after replacing a traditional spinal cord stimulation (SCS) implantable pulse generator with a next generation SCS in patients for whom traditional SCS was no longer providing adequate relief of low back and/or leg pain. Subjects (n = 19) who reported that they were no longer receiving adequate relief from traditional SCS were implanted with a next generation SCS. Eighteen additional patients who were receiving relief from traditional SCS were also followed as a control. Both groups (next generation, traditional) were assessed for low-back and limb pain (visual analog scale) and daily physical activity (wearable accelerometer) at baseline and three, six, nine and 12 months following the SCS implant. Relative to baseline, next generation SCS subjects exhibited reductions (p ≤ 0.05 for all) in low-back pain (average reduction of 22%) at every time point, in leg pain (average reduction of 23%) at every time point except six months and increased physical activity (average increase of 57%) at three, six and nine months. As expected, there were no changes in pain or physical activity in the traditional SCS subjects (p ≥ 0.1). In conclusion, pain decreased, and physical activity increased in patients receiving a next generation SCS. Physical activity may serve as an objectively measured marker of pain

Poultry Q&A

6 ppWhy do chickens bob their heads back and forth? How can baby chicks survive without a mother hen? Are fertile eggs more nutritious than nonfertile eggs? Why do chickens and turkeys have white and dark meat? In this publication you'll find the answers to these and other intriguing questions about poultry. Topics include biology, behavior, anatomy, incubation, embryology, products and food safety